Lectures: Receptor Symposium -
October 8 - 10
GPCR DIMER SYMPOSIUM
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program
Organizer:
Martin J. LohseContact: martin.lohse@virchow.uni-wuerzburg.de
Location:
Lecture Hall of the Rudolf Virchow Center - "Neubau",
Josef-Schneider-Str. 2 - Building D15
(Exact Times and Locations
are subject to change.)
October 8 - Inaugration of the new building of
the Rudolf-Virchow- Center
17:00
Welcome: Alfred Forchel,
President of the University of Würzburg
Lectures:
Matthias
Kleiner, President of the German Research Foundation,
DFG
Wolfgang Heubisch, Bavarian State
Minister of Sciences, Research and
the Arts
Fritz
Melchers, Scientific Advisory Board of the Rudolf-Virchow-Center
Handover of keys:
Dieter
Maußner, Director, Building authority of the
University of Würzburg
Reception
following
October 9 - GPCR Dimer Symposium
Location:
Seminar Room (first floor) of the Rudolf Virchow Center - "Neubau",
Josef-Schneider-Str. 2 - Building D15
(Exact Times and Locations
are subject to change.)
Introduction
9.00
Martin Lohse,
Rudolf-Virchow-Center, Würzburg
“Why receptor dimers?"
Techniques to study GPCR assemblies
9.30
Michel Bouvier, University of
Montréal
“Probing the multimeric assemblies of GPCR using multi-colour BRET
and dual BRET/BiFC approaches”
10.15
Roger Sunahara, University of
Michigan, Ann Arbor
“Modulation of high affinity
ligand binding by G proteins”
11.00
Coffee break
11.30
Moritz Bünemann, University of
Würzburg/Marburg
“Stability and extent of
receptor oligomerization analyzed by FRAP
microscopy”
12.15
Sergi Ferre, National Institute on
Drug Abuse, NIH, Bethesda
“Electrostatic interactions as key determinants of the quaternary
structure of receptor heteromers”
13:00
– 14:00
Lunch
GPCR
Dimers – yes or no, how or when?
14.00
Philippe Deterre, INSERM,
Université Pierre et Marie Curie, Paris
“Pharmacological evidences for
GPCR dimers: a skeptical view”
14.45
Klaus Peter Hofmann, Campus Charité
Mitte, Berlin
„
Mechanism of signal transfer from receptor to G protein: the
rhodopsin transducin model”
15:30
Jean Louis Banères, University of
Montpellier
“Receptor
activation in a GPCR heterodimer”
16.15 –
16:30 Coffee break
The
advance in microscopy
Lecture Hall of the Rudolf Virchow Center - "Neubau",
Josef-Schneider-Str. 2 - Building D15
(Exact Times and Locations
are subject to change.)
16:30
High Resolution
Microscopy: PALM, Zeiss Microimaging
17:00 High Sensitivity -
Single
Molecule Microscopy, Leica Microsystems
17:30 Inauguration of STED Microscope
High Resolution Microscopy: STED, Leica Microsystems
Open House of Leica Microscope
Systems – Bioimaging Center
October 10 - GPCR Dimer
Symposium
Location:
Seminar Room (first floor) of the Rudolf Virchow Center - "Neubau",
Josef-Schneider-Str. 2 - Building D15
(Exact Times and Locations
are subject to change.)
Functional consequences of GPCR dimerization
9:00
Jean-Philippe Pin, INSERM CNRS, Montpellier
“Class C GPCR dimers and
oligomers: role in G-protein activation”
9.45
Graeme Milligan, University of
Glasgow
“The role of GPCR dimerisation in cell surface delivery and trafficking”
10:30
Coffee break
11:00
Rafael Franco, Universitat de
Barcelona
“Heteromer-based pharmacology
in drug discovery”
11.45
Lakshmi A. Devi, Mount Sinai School
of Medicine, NY
“G Protein-coupled Receptor
Dimerization: Implications in Novel
Signaling and Drug Development”
12.30
Concluding discussion: What experiments to
do next
13.00
Lunch
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